Fight Colorectal Cancer gathered 35 brilliant scientists and public health professionals in Denver during the last week of January 2019. After two wonderful presentations to set the stage, we broke into groups and began a series of exercises to determine which risk factors are most critical to study, and how current and new studies can be leveraged to determine which risk factors are driving the increase in incidents of early on-set colorectal cancer. Never underestimate the power of combining simple questions, intelligent people, structured discussion, and 3M Post-it Notes. We landed on some fascinating conclusions. Thanks to Andi Dwyer, Fight CRC, and our wonderful participants from across the globe.